Fipnil Plus Spot-On Solution for Extra Large Dogs Pack of 3

Fipronil and (S)-methoprene for dogs over 40kg

Fipnil Plus contains two active ingredients that work on different stages of the flea life cycle. Fipronil is an insecticide and acaricide that treats flea infestations and tick infestations, and infestations with biting lice. (S)-methoprene inhibits the development of flea eggs, larvae and pupae, preventing the multiplication of fleas.

Against new infestations with adult fleas, the insecticidal efficacy persists for 8 weeks, and flea eggs and larvae are prevented from developing for eight weeks after application. Against ticks, the acaricidal efficacy persists for up to 4 weeks.

Key features of Fipnil Plus Spot-On Solution for Extra Large Dogs:

• For dogs weighing over 40kg: one 4.02ml pipette per dog.
• Treats fleas, ticks and biting lice: for flea infestations alone or with ticks and/or biting lice.
• Two active ingredients: fipronil 402mg and (S)-methoprene 361.8mg per pipette.
• 3 pipettes, each in its own foil sachet.
• Minimum treatment interval of 4 weeks.
• From 8 weeks of age: not for puppies under 8 weeks old.

Treating the home as well as the dog

Fleas from pets often infest the animal's basket, bedding and regular resting areas such as carpets and soft furnishings. In case of massive infestation, and at the beginning of flea control, treat these areas with a suitable insecticide and vacuum regularly. Fipnil Plus is for dogs only: never use it on cats or rabbits. See our flea and worm treatments for dogs, the other Fipnil sizes, and our guide to flea and worm treatment for UK pet owners.

Dosage

One pipette of 4.02 ml per dog weighing over 40 kg, corresponding to a minimum recommended dose of 6.7 mg/kg for fipronil and 6 mg/kg for (S)-methoprene, by topical application to the skin.

In the absence of safety studies, the minimum treatment interval is 4 weeks.

Do not use on puppies less than 8 weeks old.

How to apply

1. Hold the pipette upright. Tap the narrow part of the pipette to ensure the contents remain within the main body of the pipette.
2. Snap back the tip.
3. Part the coat on the back of the animal at the base of the neck in front of the shoulder blades until the skin is visible.
4. Place the tip of the pipette on the skin and squeeze the pipette several times to empty its contents completely and directly onto the skin in one spot.

Temporary changes to the coat (clumped/greasy hair) may be noted at the application site. Do not overdose.

It is recommended that animals are not treated during the day, but should be treated during the early evening, and that recently treated animals are not allowed to sleep with owners, especially children.

Before use

Do not use:

• In the absence of available data, on puppies less than 8 weeks old.
• On sick (e.g. systemic diseases, fever) or convalescent animals.
• In rabbits, due to a risk of adverse drug reactions or even death. In absence of studies, the use of the product is not recommended in non-target species.
• In cats. This product is specifically developed for dogs; use in cats could lead to overdosing.
• In known cases of hypersensitivity to the active substance or to any of the excipients.

Special warnings:

• Bathing/immersion in water within 2 days after application of the product and more frequent bathing than once a week should be avoided, as no study has been performed to investigate how this affects the efficacy of the product. Emollient shampoos can be used prior to treatment, but reduce the duration of protection against fleas to approximately 5 weeks when used weekly after application of the product. Weekly bathing with a 2% chlorhexidine medicated shampoo did not affect efficacy against fleas during a 6 week long study.
• There may be an attachment of a few ticks. For this reason a transmission of infectious diseases cannot be completely excluded if conditions are unfavourable.

Precautions for use in animals: Avoid contact with the animal's eyes. It is important to make sure that the product is applied to an area where the animal cannot lick it off and to make sure that animals do not lick each other following treatment.

Precautions for the person applying the product:

• This product can cause mucous membrane, skin and eye irritation. Therefore, contact of the product with mouth, skin and eyes should be avoided.
• People with a known hypersensitivity to insecticides or alcohol should avoid contact with the product.
• Avoid contents coming into contact with the fingers. If this occurs, wash hands with soap and water.
• After accidental ocular exposure the eye should be rinsed carefully with clean water.
• If the product is accidentally swallowed, seek medical advice immediately and show the package leaflet to the physician.
• Wash hands after use.
• Treated animals should not be handled until the application site is dry, and children should not be allowed to play with treated animals until the application site is dry. It is therefore recommended that animals are not treated during the day, but should be treated during the early evening, and that recently treated animals are not allowed to sleep with owners, especially children.
• Keep stored pipettes in the original packaging until ready to use. In order to prevent children from getting access to used pipettes, dispose of used pipettes immediately.
• Do not smoke, drink or eat during application.

Environment: Fipronil and (S)-methoprene may adversely affect aquatic organisms. Dogs should not be allowed to swim in watercourses for 2 days after application.

Pregnancy and lactation: The product can be used during pregnancy and lactation.

Interactions: None known.

Side effects and overdose

Side effects: Among the very rare suspected adverse reactions, transient skin reactions on the application site (skin discoloration, local hair loss, itching, redness) and general itching or hair loss have been reported after use. Excessive salivation, reversible nervous signs (increased sensitivity to stimulation, depression, other nervous signs), vomiting or respiratory symptoms have also been observed after use. If licking occurs, a brief period of excessive salivation may be observed due mainly to the nature of the carrier. If you notice any side effects, contact your vet.

Overdose: No adverse effects were observed in target animal safety studies in 8 week-old puppies, growing dogs and dogs weighing about 2 kg treated once at five times the recommended dose. The risk of experiencing adverse effects may however increase when overdosing, so animals should always be treated with the correct pipette size according to bodyweight.

Storage and disposal

• Do not store above 30°C. Store in the original package.
• Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
• Fipronil and (S)-methoprene should not enter water courses as this may be dangerous for fish and other aquatic organisms.

Active ingredients: Fipronil 402.00 mg, (S)-methoprene 361.80 mg per 4.02 ml pipette.

Other ingredients: Butylhydroxyanisole (E320) 0.80 mg, Butylhydroxytoluene (E321) 0.40 mg, Ethanol anhydrous, Polysorbate 80 (E433), Povidone, Diethylene glycol monoethyl ether.

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We cannot guarantee the Patient Information Leaflet is accurate and is for reference only.