Do not take Liberize Sildenafil 50mg Tablets if you:
- Are allergic to sildenafil or any of the other ingredients of this medicine.
- Take any nitrate medicine for chest pain or heart failure.
- Take amyl nitrite, so called "poppers" as recreational drugs.
- Take ritonavir for the treatment of HIV.
- Take riociguat (or other guanylate cyclase stimulators) for high blood pressure in the lungs.
- Have been advised by your doctor to avoid sexual activity because of a problem with your heart or blood vessels.
- Have a severe heart problem such as a recent heart attack or stroke (within the last 6 months), unstable angina (chest pain) or severe cardiac failure (reduced pumping capacity of the heart).
- Have a severe liver problem.
- Have low blood pressure (below 90/50 mmHg) which can cause symptoms such as tiredness, dizziness, light-headedness, feeling sick, clammy skin, depression, loss of consciousness, or blurry vision.
- Have ever had severe vision loss because of nerve damage in the eyes, such as non-arteritic anterior ischaemic optic neuropathy (NAION); or have a rare inherited eye disease, such as retinitis pigmentosa.
- Have a deformed penis.
- Are a woman.
- Do not have an erection problem.
- Are under 18 years of age.
Warnings and precautions
You should schedule a health check-up with your doctor as soon as possible within the first 6 months of starting to use Liberize Sildenafil 50mg Tablets to ensure that your erection problems are not caused by any serious health condition.
Erectile dysfunction may be an early sign of:
- Cardiovascular disease
- Diabetes
- High blood pressure
- High cholesterol
Talk to your doctor about your problems if you have not already done so.
Cardiovascular risk factors
Sexual activity can put a strain on your heart. Talk to your doctor before taking Liberize Sildenafil 50mg Tablets if you:
- Get very breathless or feel any pain in the chest with light or moderate activity (e.g. walking briskly for 20 minutes or climbing two flights of stairs). Your doctor may need to check whether your heart can take the additional strain of having sex.
- Have a problem with a valve in your heart (valvular heart disease).
- Have a disease in which the heart muscle becomes inflamed and does not work as well as it should (cardiomyopathy).
- Have an irregular heartbeat (arrhythmia).
- Have had surgery to improve blood flow to your heart, or you have high blood pressure which is now adequately treated.
- Have high blood pressure that is not controlled.
Other risk factors:
Talk to your doctor before taking Liberize Sildenafil 50mg Tablets if you:
- Have ever had an erection that lasted more than 4 hours (priapism). Some conditions can increase the probability of having a persistent erection, such as sickle cell anaemia (an abnormality of red blood cells), leukaemia (cancer of blood cells), or multiple myeloma (cancer of bone marrow). Use of impotence medicines may increase the risk of priapism. Long lasting erection may cause damage to the tissue in the penis and permanent loss of ability to have an erection.
- Have a stomach ulcer or a bleeding disorder (such as haemophilia).
- Have previously been diagnosed with mild to moderate liver disease, or severe kidney problems. Liberize Sildenafil 50mg Tablets may not be suitable for you, you should consult your doctor before taking Liberize Sildenafil 50mg Tablets.
If you experience any sudden visual defect you should stop taking Liberize Sildenafil 50mg Tablets and contact your doctor immediately. Cases of visual defects have been reported when using sildenafil.
Children and adolescents
This medicine should not be given to children or adolescents under the age of 18 years.
Other medicines and Liberize Sildenafil 50mg Tablets
Tell your pharmacist or doctor if you are taking, have recently taken or might take any other medicines. Some medicines may be affected by Liberize Sildenafil 50mg Tablets or they may affect how Liberize Sildenafil 50mg Tablets works and this may result in side effects.
Do not use Liberize Sildenafil 50mg Tablets if you take:
- Nitrate medicines: Do not take Liberize Sildenafil 50mg Tablets if you are taking nitrate medicines (such as glyceryl trinitrate, isosorbide mononitrate, isosorbide dinitrate) against chest pain (angina pectoris) or heart failure or "poppers" as recreational drugs (nitric oxide donors (such as amyl nitrite), nicorandil or sodium nitroprusside). This is because these substances could lead to a dangerous fall in blood pressure if taken together with Liberize Sildenafil 50mg Tablets.
- Riociguat: Do not take Liberize Sildenafil 50mg Tablets if you are taking a medicine called riociguat (or other medicines of a group called guanylate cyclase stimulators). Riociguat is used to treat high blood pressure in the lungs and can lead to a dangerous fall in blood pressure if taken together with Liberize Sildenafil 50mg Tablets.
- Medicines to treat HIV-infections: Ritonavir is a medicine used to treat HIV-infections. Do not take Liberize Sildenafil 50mg Tablets if you are taking ritonavir since this combination can lead to a dangerous fall in blood pressure.
Talk to your pharmacist or doctor before using Liberize Sildenafil 50mg Tablets if you are taking:
- Medicines to treat fungal infections and antibiotics: Medicines to treat fungal infections called itraconazole or ketoconazole and an antibiotic called erythromycin increase the concentration of Liberize Sildenafil 50mg Tablets in the body and may result in side effects. You should contact your doctor before taking Liberize Sildenafil 50mg Tablets if you are using these medicines.
- Heartburn treatment: The medicine to treat heartburn, cimetidine, increases the concentration of Liberize Sildenafil 50mg Tablets in the body and may result in side effects. You should contact your doctor before taking Liberize Sildenafil 50mg Tablets.
- Other treatments for erectile dysfunction: The safety and efficacy of combinations of Liberize Sildenafil 50mg Tablets with other treatments for erectile dysfunction have not been studied and this combination is therefore not recommended.
- Alpha-blockers used to treat urinary problems or high blood pressure: Alpha-blockers used to treat urinary problems due to enlarged prostate (such as alfuzosin, doxazosin or tamsulosin) may lead to dizziness, light-headedness, nausea, fainting, lack of concentration, or blurred vision due to low blood pressure (symptomatic hypotension).
- Medicines containing sacubitril/valsartan, used to treat heart failure: You should contact your doctor or pharmacist before taking Liberize Sildenafil 50mg Tablets.
Liberize Sildenafil 50mg Tablets with food and drink and alcohol
Liberize Sildenafil 50mg Tablets can be taken with or without food. When this medicine is taken after a high-fat meal, it may take a little longer to start working. Do not take Liberize Sildenafil 50mg Tablets with grapefruit or grapefruit juice, because this can affect how the medicine works.
Drinking excessive alcohol can temporarily reduce your ability to achieve an erection. To get a benefit from the medicine, you are advised not to drink large amounts of alcohol before sexual activity.
Pregnancy, breast-feeding and fertility
This medicine should not be used by women.
Driving and using machines
Liberize Sildenafil 50mg Tablets can cause dizziness and can affect your vision. Do not drive or use machines if you suffer from these side effects after taking this medicine.
