Do not take Diphenhydramine Hydrochloride 50mg Tablets if:
- You are allergic to Diphenhydramine Hydrochloride or any of the other ingredients (listed in the ingredients section).
- You have a peptic ulcer.
- You have a blockage between your stomach and small intestine.
Talk to your doctor or pharmacist before taking Diphenhydramine Hydrochloride 50mg Tablets if you suffer from:
- Myasthenia gravis (abnormal muscle function).
- Seizures or epilepsy.
- Asthma, bronchitis, or Chronic Obstructive Pulmonary Disease (COPD).
- Narrow angle glaucoma.
- An enlarged prostate.
- Difficulty urinating.
- Moderate to severe liver or kidney problems.
- You are elderly, particularly if you also suffer from confusion.
Other medicines and Diphenhydramine Hydrochloride 50mg Tablets: Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. In particular, tell your doctor or pharmacist if you are taking any of the following:
- Other antihistamines, including those used on your skin and in cough and cold medicines.
- Tranquillisers or anxiolytics (sedatives) used to treat anxiety (e.g., diazepam).
- Hypnotics (e.g., nitrazepam) used to help you sleep better.
- Monoamine oxidase inhibitors (MAOIs) for depression (e.g., phenelzine) or if you have stopped taking an MAOI within the last two weeks.
- Metoprolol (a beta blocker) used to treat high blood pressure, angina, irregular heartbeat or overactive thyroid.
- Venlafaxine used to treat depression.
- Antimuscarinics which relax smooth muscles and are used for example in Parkinson’s Disease, irritable bowel syndrome and incontinence (e.g., procyclidine, trihexyphenidyl, atropine, oxybutinin, fesoterodine).
- Tricyclic antidepressants (e.g., imipramine, amitriptyline).
Diphenhydramine Hydrochloride 50mg Tablets with alcohol: Do not drink alcohol if you are taking this medicine. Pregnancy, breast-feeding and fertility: If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Driving and using machines: This medicine causes drowsiness and sedation and may also cause dizziness, blurred vision, disturbance in attention and slower reaction times. Do not drive or operate machinery while you are affected in this way. Diphenhydramine Hydrochloride 50mg Tablets contain lactose: This medicine contains lactose. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine. Possible Side Effects: Like all medicines, this medicine can cause side effects, although not everybody gets them. Stop taking the tablets IMMEDIATELY and contact your doctor if you experience signs of an allergic reaction:
- Difficulty breathing or shortness of breath.
- Swelling of the face, mouth or throat.
- Rash, hives (itchy, raised red weals).
Tell your doctor straight away if you notice any of the following effects:
- Fever, chills, sore throat, infections (these may be signs of a blood disorder).
- Faster heartbeat, irregular heartbeat.
- Fits, difficulty making or controlling movements.
Tell your doctor, pharmacist or nurse if you suffer from any of the following other effects: Common effects (may affect up to 1 in 10 people):
- Sedation, drowsiness, dizziness, unsteadiness, disturbance in attention.
- Dry mouth.
- Fatigue.
Other effects:
- Palpitations (feeling your heartbeat).
- Headache, tingling or numbness (pins and needles).
- Depression, sleep disturbances.
- Confusion, excitation (e.g., increased energy, restlessness, nervousness - the elderly are more likely to experience these effects).
- Difficulty urinating or inability to pass urine.
- Thicker bronchial mucus.
- Blurred vision.
- Feeling or being sick, stomach problems.
- Muscle twitching.
