Prinocate Spot-on-Solution Medium Dog 100/25mg (4 – 10kg) Pack of 3

Prinocate Spot-on-Solution Medium Dog 100/25mg (4 – 10kg) Pack of 3 combines the powerful active ingredients imidacloprid and moxidectin to provide effective and long-lasting protection. Its easy-to-apply spot-on format makes monthly treatment simple, helping to keep your dog healthy and comfortable.

Comprehensive Parasite Control

This advanced solution is indicated for the treatment and prevention of a wide range of common canine parasites, including:

• Fleas: Not only treats existing flea infestations but also provides prevention for up to 4 weeks, helping to break the flea life cycle in your home.
• Biting Lice: Effectively eliminates biting lice.
• Mites: Targets ear mites (Otodectes cynotis), sarcoptic mange (Sarcoptes scabiei var. canis), and demodicosis (Demodex canis), which can cause significant skin irritation and discomfort.
• Heartworm: Prevents heartworm disease (caused by Dirofilaria immitis), a serious and potentially fatal condition.
• Gastrointestinal Worms: Treats and controls various worms including roundworm (Toxocara canis, Toxascaris leonina), hookworm (Ancylostoma caninum, Uncinaria stenocephala), and whipworm (Trichuris vulpis).
• Other Parasites: Also effective against cutaneous dirofilariosis (skinworm - Dirofilaria repens), lungworm (Angiostrongylus vasorum, Crenosoma vulpis), spirocercosis (Spirocerca lupi), Eucoleus (Capillaria) boehmi, and the eye worm (Thelazia callipaeda).

By preventing and treating these parasites, Prinocate Spot-on-Solution Medium Dog 100/25mg (4 – 10kg) Pack of 3 can also be used as part of a treatment strategy for flea allergy dermatitis (FAD), providing relief from itching and discomfort caused by allergic reactions to flea bites. Trust Weldricks Pharmacy for reliable pet health solutions, delivered discreetly to your door with free UK delivery on orders over £40.

Prinocate Spot-on-Solution Medium Dog 100/25mg (4 – 10kg) Pack of 3 is for spot-on use and external application only. Apply topically to the skin between the shoulder blades.

General Application Steps:

1. Remove one pipette from the package.
2. Hold the applicator pipette in an upright position.
3. Twist and pull the cap off.
4. Turn the cap around and place the other end of the cap back on the pipette.
5. Push and twist the cap to break the seal, then remove the cap from the pipette.

Application for dogs up to 10kg

With the dog standing still, part the coat between the shoulder blades until the skin is visible. The veterinary medicinal product should only be applied to undamaged skin. Place the tip of the pipette on the skin and squeeze firmly several times to empty the contents directly onto the skin.

Dosage Schedule:

The recommended minimum doses are 10 mg/kg bodyweight imidacloprid and 2.5 mg/kg bodyweight moxidectin, equivalent to 0.1 ml/kg bodyweight.

For medium dogs (4-10 kg), use the imidacloprid/moxidectin 100 mg/25 mg spot-on solution. Each 1ml pipette is designed to deliver a dose range of 10-25 mg/kg bodyweight imidacloprid and 2.5-6.25 mg/kg bodyweight moxidectin.

The treatment schedule should be based on individual veterinary diagnosis and on the local epidemiological situation. One treatment prevents future flea infestation for 4 weeks. For conditions like flea allergy dermatitis (FAD), monthly intervals are recommended.

For specific conditions, follow veterinary advice:

• Biting Lice: A single dose should be administered. A further veterinary examination 30 days after treatment is recommended.
• Ear Mite Infestation: A single dose. Gently remove loose debris from the external ear canal. Do not apply directly to the ear canal. A further veterinary examination 30 days after treatment is recommended.
• Sarcoptic Mange: A single dose administered twice, 4 weeks apart.
• Demodicosis: Single dose every 4 weeks for 2 to 4 months. Severe cases may require more prolonged and frequent treatment (e.g., once a week at veterinarian's discretion). Continue until skin scrapings are negative on at least 2 consecutive monthly occasions.
• Heartworm Disease and Cutaneous Dirofilariosis Prevention: Apply at regular monthly intervals during the time of the year when mosquitoes are present, or throughout the year (at least 1 month before first expected exposure to 1 month after last exposure).
• Treatment of Microfilariae (D. immitis): Administer monthly for two consecutive months.
• Treatment of Cutaneous Dirofilariosis (skin worm) (adult stages of D. repens): Administer monthly for six consecutive months.
• Reduction of Microfilariae (skin worm) (D. repens): Administer monthly for four consecutive months.
• Angiostrongylus vasorum Treatment and Prevention: A single dose. Further veterinary examination 30 days after treatment is recommended. For prevention in endemic areas, regular monthly applications.
• Crenosoma vulpis Treatment: A single dose should be administered.
• Spirocercosis Prevention: Administer monthly.
• Eucoleus (Capillaria) boehmi Treatment: Administer monthly for two consecutive months. Prevent auto-coprophagia between treatments.
• Thelazia callipaeda Treatment: A single dose should be administered.
• Roundworm, Hookworm, and Whipworm Treatment: Monthly treatment can significantly reduce re-infection risk. In non-endemic areas, can be part of seasonal prevention.

Special Warnings:

• Do not use in puppies under 7 weeks of age.
• Do not use in cases of hypersensitivity to the active substances or to any of the excipients.
• Do not use in dogs classified as Class 4 for heartworm disease, as safety has not been evaluated for this group.
• For cats and ferrets, use the corresponding veterinary medicinal product specifically designed for them (e.g., 0.4 ml for small cats and ferrets). Do not use dog Prinocate on cats or ferrets.
• Do not use on canaries.
• Brief contact with water on one or two occasions between monthly treatments is unlikely to significantly reduce efficacy.
• For animals weighing less than 1 kg, treatment should be based on a benefit-risk assessment.
• There is limited experience on the use of this product in sick and debilitated animals, so a veterinary assessment is needed.
• Care should be taken that the contents of the pipette or the applied dose do not come into contact with the animal's eyes or mouth, or other animals' eyes/mouths. Prevent treated animals from grooming each other.
• Product should not be applied to damaged skin.
• If animal licks the application site immediately after treatment, salivation may occur, which is not a sign of intoxication and disappears within minutes. Correct application minimises licking.

Special precautions to be taken by the person administering the veterinary medicinal product to animals:

• Keep pipettes in original packaging until ready for use and dispose of used pipettes immediately to prevent children from access.
• Do not ingest. In case of accidental ingestion, seek medical advice immediately and show the package leaflet or label to a physician.
• People with known hypersensitivity to benzyl alcohol, imidacloprid, or moxidectin should administer the product with caution.
• In very rare cases, the product may cause skin sensitisation or transient skin reactions (numbness, irritation, burning/tingling sensation) or respiratory irritation in sensitive individuals.
• If product accidentally gets into eyes, flush thoroughly with water.
• Avoid contact with skin, eyes, or mouth. In case of accidental spillage onto skin, wash off immediately with soap and water. Wash hands thoroughly after use. If skin or eye symptoms persist, seek medical advice.
• Do not eat, drink, or smoke during application.
• Treated animals should not be handled, especially by children, until the application site is dry. Apply in the evening. Recently treated animals should not sleep in the same bed as their owner, especially children.

Special precautions for the protection of the environment:

• The product should not enter water courses as moxidectin is highly toxic to aquatic organisms.
• Dogs should not be allowed to swim in surface waters for 4 days after treatment.

Other precautions:

• The solvent in the product may stain or damage certain materials including leather, fabrics, plastics, and finished surfaces. Allow the application site to dry before permitting contact with such materials.

Pregnancy and lactation:

The safety of the product has not been established during pregnancy and lactation. Laboratory studies with active ingredients in rats and rabbits produced no evidence of teratogenic, foetotoxic, or maternotoxic effects.

Interaction with other medicinal products and other forms of interaction:

During treatment, no other antiparasitic macrocyclic lactone should be administered. No interactions with routinely used veterinary medicinal products or procedures have been observed. Safety when administered on the same day as an adulticide for adult heartworms has not been evaluated.

Adverse Events (Dogs):

• Common (1 to 10 animals / 100 animals treated): Diarrhoea, vomiting, cough, dyspnoea (abnormal breathing), tachypnoea (hyperventilation), inappetence, lethargy, salivation (if animal licks application site).
• Rare (1 to 10 animals / 10,000 animals treated): Vomiting, application site greasy fur, application site erythema (redness), hypersensitivity reaction.
• Very Rare (<1 animal / 10,000 animals treated): Behavioural disorders (e.g., agitation), inappetence, lethargy, neurological signs (e.g., ataxia, tremors, ocular signs, abnormal respiration, salivation, vomiting).
• Undetermined frequency: Pruritus (itching).

Each 1 ml pipette of Prinocate Spot-on-Solution Medium Dog 100/25mg (4 – 10kg) Pack of 3 contains:

• Active Substances:
  • Imidacloprid: 100 mg
  • Moxidectin: 25 mg
• Excipients:
  • Butylhydroxytoluene (E 321): 1 mg
  • Benzyl alcohol (E 1519): 807 mg

The solution is clear, slightly yellow to yellow or to brownish yellow.