Zelys 1 Chewable Tablet 10mg

What Zelys 1 Chewable Tablet 10mg Does for Your Dog

Zelys 1 Chewable Tablet 10mg is a prescription-only veterinary medicine specifically formulated to support dogs suffering from canine congestive heart failure, including conditions originating from valvular insufficiency or dilated cardiomyopathy. Its active ingredient, Pimobendan, works to enhance heart function and improve circulation, offering essential relief and support to your beloved pet's health.

Key Benefits of Zelys 1 Chewable Tablet 10mg

• Improved Cardiac Function: Pimobendan helps to improve the pumping ability of your dog's heart, which can significantly ease the symptoms associated with heart failure.
• Easy Administration: Designed as a chewable tablet, Zelys 1 Chewable Tablet 10mg is often more palatable and easier for dogs to take, making treatment less stressful for both pets and owners.
• Targeted Treatment: This medication is precisely formulated to address specific canine heart conditions, ensuring your dog receives appropriate and effective care under veterinary supervision.

Understanding Pimobendan for Dogs

Pimobendan, the active substance in Zelys 1 Chewable Tablet 10mg, functions as a cardiac stimulant with vasodilatatory properties. It enhances the heart's contractility and dilates blood vessels, which reduces the workload on the heart and improves blood flow throughout the body. This dual action is vital for managing canine heart failure symptoms and improving overall quality of life.

As a Veterinary Medicinal Product (POM-V), Zelys 1 Chewable Tablet 10mg can only be supplied with a valid prescription from your veterinary surgeon. Weldricks Pharmacy is a trusted UK-regulated pharmacy, providing a convenient and professional service for dispensing your dog's prescription medications with care and discreet delivery.

How to Administer Zelys 1 Chewable Tablet 10mg

Always follow your veterinary surgeon’s instructions carefully regarding dosage and frequency. Do not exceed the recommended dosage.

• Determine your dog’s bodyweight accurately before treatment to ensure correct dosage.
• The tablets should be administered orally at a dose range of 0.2 mg to 0.6 mg pimobendan per kg body weight per day.
• The preferable daily dose is 0.5 mg pimobendan per kg body weight, divided into two administrations (0.25 mg/kg body weight each).
• Give one half of the dose in the morning and the other half approximately 12 hours later.
• Each dose should be given approximately one hour before feeding for optimal absorption.
• Tablets are chewable and can be given spontaneously by the animal or placed behind the lingual torus (back of the tongue).
• Zelys 10mg chewable tablets are divisible into two equal parts, making accurate dosing easier for various dog weights. For example, a 40 kg dog would typically receive one 10 mg chewable tablet in the morning and one 10 mg chewable tablet in the evening.
• This product may be combined with a diuretic treatment such as furosemide, as advised by your vet.

In case of overdose, symptoms like increased heart rate, vomiting, apathy, ataxia, heart murmurs, or hypotension may occur. If this happens, reduce the dosage and seek immediate veterinary advice for symptomatic treatment.

Important Warnings and Precautions

Special Precautions for Use in Animals:

• Regularly test blood glucose in dogs with existing diabetes mellitus during treatment.
• Monitoring of cardiac function and morphology is recommended in animals treated with Pimobendan.
• The chewable tablets are flavoured. To avoid accidental ingestion, store tablets out of reach of animals.

Contraindications:

• Do not use Pimobendan in hypertrophic cardiomyopathies or in diseases where an improvement in cardiac output cannot be achieved for functional or anatomical reasons (e.g., aortic stenosis).
• Do not use in dogs with severe impairment of liver function, as Pimobendan is metabolised mainly via the liver.
• The safety of Zelys 1 Chewable Tablet 10mg has not been assessed in pregnant or nursing bitches. Use only according to a benefit/risk assessment by the responsible veterinarian.

Special Precautions to be Taken by the Person Administering the Veterinary Medicinal Product:

• Accidental ingestion, especially by a child, may lead to symptoms such as rapid heart rate (tachycardia), low blood pressure (orthostatic hypotension), facial flushing, and headaches.
• Unused part-tablets should be returned to the open blister space or bottle and inserted back into the outer packaging.
• Keep out of sight and reach of children.
• Close the bottle tightly with the cap directly after removing the required number of tablets or part-tablets.
• In case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician.
• Wash hands thoroughly after use.

Adverse Reactions:

While generally well-tolerated, rare side effects may occur. The frequency of adverse reactions is defined as follows:

• Rare (1 to 10 animals in 10,000 treated): A slight increase in heart rate (positive chronotropic effect) and vomiting can occur. These are dose-dependent and may be avoided by reducing the dose.
• Rare: Transient diarrhoea, anorexia (loss of appetite), or lethargy have been observed.
• Very rare (less than 1 animal in 10,000 treated): Signs of effects on primary haemostasis (e.g., small red or purple spots on mucous membranes, subcutaneous haemorrhages) may be observed, which typically disappear upon treatment withdrawal.
• Very rare: An increase in mitral valve regurgitation has been observed during chronic Pimobendan treatment in dogs with mitral valve disease.

Zelys 1 Chewable Tablet 10mg Ingredients

Each tablet contains:

• Active substance: Pimobendan 10 mg

Excipients:

• Silica colloidal anhydrous
• Stearic acid
• Copovidone
• Croscarmellose sodium
• Malic acid
• Maize starch
• Cellulose microcrystalline
• Lactose monohydrate
• Dried Yeast (from Saccharomyces cerevisiae)
• Pig liver powder