Ovesse 1mg/g Vaginal Cream 15g + Applicator

Effective Relief for Menopausal Vaginal Symptoms

As women age, particularly after menopause, a natural drop in oestrogen levels can lead to the 'Genitourinary Syndrome of Menopause' (GSM). This can cause the vaginal walls to become thinner, drier, and less elastic, resulting in uncomfortable symptoms.

Ovesse 1mg/g Vaginal Cream 15g + Applicator is a local Hormone Replacement Therapy (HRT) designed to effectively combat these changes. By delivering estriol directly to the vagina, it helps to replenish the oestrogen levels where they are needed most, alleviating a range of discomforts including:

• Vaginal dryness and soreness
• Irritation, itching, or burning sensations
• Painful sexual intercourse

This targeted approach helps to restore the natural balance and comfort of the vaginal area, allowing you to manage your everyday health confidently. Ovesse 1mg/g Vaginal Cream 15g + Applicator is specifically formulated for postmenopausal women aged 50 years and above who have not had a period for at least 1 year.

Why Choose Ovesse Vaginal Cream?

Choosing Ovesse 1mg/g Vaginal Cream 15g + Applicator means opting for a trusted solution that delivers oestrogen locally, directly addressing the root cause of your symptoms. Our customers often appreciate the discreet and easy-to-use applicator, ensuring precise dosage and application for optimal results.

At Weldricks Pharmacy, we are committed to providing accessible and professional healthcare. With Ovesse 1mg/g Vaginal Cream 15g + Applicator, you can take a proactive step towards relieving menopausal vaginal discomfort and improving your quality of life. For more support and information, explore our menopause care products and women's health section.

• Active substance: Estriol (1 milligram per gram of cream).
• Other ingredients: Chlorhexidine dihydrochloride, octyldodecanol, cetyl palmitate, glycerin, cetyl alcohol, stearyl alcohol, polysorbate 60, sorbitan stearate, lactic acid, sodium hydroxide and purified water.

• How much to use
  • Initial dose: 1 applicator filled up to the red ring mark (0.5 mg estriol in 0.5 g of cream) a day for 2 weeks.
  • Maintenance dose: 1 applicator filled up to the red ring mark twice a week (3 or 4 days between each dose).
• Restarting treatment after a break

  You can restart using Ovesse 1mg/g Vaginal Cream 15g + Applicator at any time provided it is still suitable and your overall health is unchanged.

  • If you are still experiencing symptom relief after a break from treatment with Ovesse 1mg/g Vaginal Cream 15g + Applicator, it is recommended that treatment is restarted at the maintenance dose.
  • If you are experiencing bothersome symptoms again after a break from treatment with Ovesse 1mg/g Vaginal Cream 15g + Applicator, it is recommended to restart treatment at the initial daily dose regimen for 2 weeks, followed by the twice weekly maintenance dose.

  Do NOT use more than the recommended dose.

• How to apply the cream

  Ovesse 1mg/g Vaginal Cream 15g + Applicator comes in a pack together with a clear plastic applicator. Use the applicator to apply the cream in the vagina. A good time to do this is before going to bed. The applicator has a red ring marked on the body. Fill the applicator up to the red ring mark with Ovesse vaginal cream to get the correct dose.

  Follow these instructions:

  1. Remove the cap from the tube and turn the cap upside down. Then use the sharp point to open the tube.
  2. Screw the end of the applicator onto the tube.
  3. Squeeze the tube to fill the applicator with the cream up to the red ring mark (the plunger will stop at the red ring mark).
  4. Unscrew the applicator from the tube and put the cap back on the tube.

  To apply the cream, lie down, put the end of the applicator deep into your vagina and slowly push the plunger all the way in.

• Cleaning the applicator
  • After use, pull the plunger out of the barrel.
  • Wash the plunger and barrel in hand hot, soapy water.
  • Do not use detergents.
  • Rinse well with clean water afterwards.
  • Do not put the applicator in boiling water.

  Ovesse 1mg/g Vaginal Cream 15g + Applicator is easy to remove with water. Speak to your pharmacist if you experience any difficulties with using the vaginal applicator.

• If you use more Ovesse 1mg/g Vaginal Cream 15g + Applicator than you should or if you swallow it accidentally

  If someone has swallowed some cream by accident, or too much cream is applied at any time, there is no need to worry. However, you should talk to your doctor or pharmacist. The person may feel sick or be sick. Women may have some vaginal bleeding after a few days.

• If you forget to use Ovesse 1mg/g Vaginal Cream 15g + Applicator

  If you forget a dose, use the medicine as soon as you remember. Do not use a double dose to make up for a forgotten dose.

• If you stop using Ovesse 1mg/g Vaginal Cream 15g + Applicator

  You can stop using Ovesse 1mg/g Vaginal Cream 15g + Applicator at any time, however, symptoms may return when you stop. Speak to your doctor if you want to try an alternative treatment.

• If you need to have surgery

  If you are going to have surgery, tell the surgeon that you are using Ovesse 1mg/g Vaginal Cream 15g + Applicator. You may need to stop using Ovesse 1mg/g Vaginal Cream 15g + Applicator about 4 to 6 weeks before the operation to reduce the risk of a blood clot (see section 2, Blood clots in a vein). Ask your doctor when you can start using Ovesse 1mg/g Vaginal Cream 15g + Applicator again.

• Always use this medicine exactly as described in this leaflet or as your pharmacist has told you.
• Keep this leaflet. You may need to read it again.
• Ask your pharmacist if you need more information or advice.
• If you get any side effects, talk to your pharmacist. This includes any possible side effects not listed in this leaflet. See Section 4.
• Your symptoms may take a few months to improve. Talk to your doctor or pharmacist if your symptoms worsen at any point, or if there has not been any improvement in your symptoms after 3 months of treatment.

Do not use Ovesse 1mg/g Vaginal Cream 15g + Applicator if you:

• Are allergic (hypersensitive) to estriol or any of the other ingredients of Ovesse (listed in Section 6).
• Have or have ever had womb or ovarian cancer, or you have symptoms such as vaginal bleeding, or pain, bloating or swelling in your lower abdomen or pelvis that you have not told your doctor about.
• Have had any vaginal or genital bleeding since your periods stopped due to the menopause.
• Have recent or suspected endometrial hyperplasia (or e.g., if you have been referred for an ultrasound of your womb and are awaiting the results).
• Have any change in the look/feel of the vulval area such as thickening or a lump, or if you have noticed any shrinking or scarring in this area.
• Have previously been treated with systemic oestrogen only HRT (without progestogen) and you have not had your womb removed (hysterectomy).
• Have a condition called “vulval dermatoses” or you have any genital skin disorders such as severe vaginal itching or itchy patches or rash. Your pharmacist will ask questions to confirm if the level of itching is a sign of something other than genitourinary syndrome of menopause.
• Have a current vaginal infection before starting treatment.
• Have or have ever had breast cancer, or if you are suspected of having it.
• Have or have ever had a blood clot in a vein (thrombosis), such as in the legs (deep venous thrombosis) or the lungs (pulmonary embolism).
• Have or recently have had a disease caused by blood clots in the arteries, such as a heart attack, stroke or angina.
• Have a blood clotting disorder (such as protein C, protein S, or antithrombin deficiency).
• Have or ever have had a liver disease and your liver function tests have not returned to normal.
• Have a rare blood problem called “porphyria” which is passed down in families (inherited).

You may need to see your doctor before using Ovesse 1mg/g Vaginal Cream 15g + Applicator if any of the following apply to you. Tell your pharmacist if you:

• Are receiving a type of HRT (including tablets or patches) that circulates in the blood.
• Have a history of endometriosis.
• Have a history of endometrial hyperplasia.
• Are switching from another vaginal oestrogen HRT.

Warnings and precautions

Talk to your doctor or pharmacist if any vaginal infection develops while you are using Ovesse 1mg/g Vaginal Cream 15g + Applicator.

Stop using Ovesse 1mg/g Vaginal Cream 15g + Applicator and see a doctor immediately if you notice any of the following during treatment:

• Any of the conditions mentioned in the ‘Do not use Ovesse’ section.
• Any new vaginal bleeding, spotting or itching.
• If you have endometriosis and your symptoms have come back.
• Swollen face, tongue and/or throat and/or difficulty swallowing or hives, together with difficulty in breathing which are suggestive of angioedema.

You must also seek prompt advice from your doctor if you notice any of the following during treatment:

• Yellowing of your skin or the whites of your eyes (jaundice). These may be signs of a liver disease.
• A large rise in your blood pressure (symptoms may be headache, tiredness, dizziness).
• Migraine-like headaches which happen for the first time.
• If you become pregnant.

Tell your doctor you are using this medicine if you have or have ever had any of the following problems, and seek advice from them if any of these conditions return or get worse during treatment:

• Uterine fibroids (leiomyoma).
• Increased risk of developing blood clots (see "Blood clots in a vein (thrombosis)").
• Increased risk of getting an oestrogen-sensitive cancer such as womb, ovarian or breast cancer (e.g. having a mother, sister or grandmother who has had any of these cancers).
• High blood pressure.
• A liver disorder, such as a benign liver tumour.
• Diabetes.
• Gallstones.
• Migraine or severe headaches.
• Systemic lupus erythematosus, SLE (a disease of the immune system that affects many organs of the body).
• Epilepsy.
• Asthma.
• Otosclerosis (a disease affecting the eardrum and hearing).
• A very high level of fat in your blood (triglycerides).
• Fluid retention due to cardiac or kidney problems.
• Hereditary or acquired angioedema.

General Information – Risks associated with HRT

Ovesse 1mg/g Vaginal Cream 15g + Applicator is a local vaginal HRT. Other HRT medicines which circulate in the blood and are used to treat hot flushes and other menopausal symptoms are known as systemic HRT. These are known to increase the risk of some conditions occurring, especially when used for a long time. It is thought that the risk of these conditions may not increase by as much with Ovesse as with systemic HRT, but this is not known for sure. You should speak with your pharmacist or doctor if you are concerned.

• Breast cancer: Evidence suggests that using Ovesse does not increase the risk of breast cancer in women who had no breast cancer in the past. It is not known if Ovesse can be safely used in women who had breast cancer in the past.
• Ovarian cancer.
• Blood clots in a vein (thrombosis).
• Heart disease (heart attack): For women taking oestrogen-only therapy there is no increased risk of developing heart disease.
• Stroke.

Taking other medicines

Tell your doctor or pharmacist if you are taking or have recently taken any other medicines including medicines obtained without a prescription, herbal medicines or other natural products. Ovesse 1mg/g Vaginal Cream 15g + Applicator is used for a local treatment in the vagina and is not likely to affect other medicines. Ovesse 1mg/g Vaginal Cream 15g + Applicator may affect other vaginally applied treatments. Ask your pharmacist for advice if you are unsure.

Pregnancy and breast-feeding

Women who are pregnant or breast-feeding should not use Ovesse 1mg/g Vaginal Cream 15g + Applicator.

Driving and using machines

Ovesse 1mg/g Vaginal Cream 15g + Applicator has no or little effect on the ability to drive or use machines.

Ovesse 1mg/g Vaginal Cream 15g + Applicator contains cetyl alcohol and stearyl alcohol. These may cause local reactions.